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CD40 抗体

The 小鼠 单克隆 anti-CD40 antibody (Clone G28-5) (ABIN6253105) specifically detects CD40 in FACS. The antibody is reactive with 人, Cynomolgus, Baboon 和 猕猴 samples.
产品编号 ABIN6253105
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD40 抗体 (ABIN6253105)

抗原

See all CD40 抗体
CD40

适用

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人, Cynomolgus, Baboon, 猕猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD40 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

G28-5
  • 原理

    CD40 Unconjugated Antibody

    产品特性

    The clone G28-5 is specific for CD40 B cell surface antigen. It is a 48 kD type I glycoprotein and a member of the tumor necrosis factor receptor superfamily. CD40 is the receptor for CD40 ligand (CD40L), a molecule predominantly expressed by activated CD4+ T cells. The CD40 on B cells and CD40L (CD154) on activated helper T cells are co-stimulatory molecules whose interaction is required for the proliferation and immunoglobulin (Ig) class switching of antigen-activated B cells.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human tonsillar lymphocytes

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    CD40

    别名

    CD40

    UniProt

    P25942

    途径

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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