TAB3 抗体 (N-Term)
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Quick Overview for TAB3 抗体 (N-Term) (ABIN6252829)
抗原
See all TAB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Protein A purified antibody
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免疫原
- A recombinant protein fragment from the N-terminal region of human TAB3 was used as the immunogen for this antibody.
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibody
TAB3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 361-712) antibodyTAB3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) antibodyTAB3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyVerified TAB3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (Internal Region) antibodyTAB3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3) (AA 50-100) antibodyTAB3 适用: 人, 小鼠, 犬, 小鸡, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 4-8 μg/mL
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
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别名
- TAB3
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背景
- TAB3, a TAB2-like protein, is a mediator of TAK1 activation in IL-1 and TNF signaling. IL-1 and TNF are cytokines involved in the inflammation process, initiating signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (MAPKs). TAB3 functions as an adapter, linking TAK1 and TRAF6 or TRAF2. This kinase complex phosphorylates IkB, which keeps NF-kB inactive and sequestered in the cytoplasm. Phosphorylation leads to IkB degradation, activating NF-kB, which translocates to the nucleus, binds to DNA response elements and can begin multiple signaling cascades.
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基因ID
- 257397
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UniProt
- Q8N5C8
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-
