TNFSF15 抗体
Quick Overview for TNFSF15 抗体 (ABIN6252817)
抗原
See all TNFSF15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human partial recombinant protein was used as the immunogen for this TL1A antibody.
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亚型
- IgG1 kappa
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 161-251) antibody
TNFSF15 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 兔 Monoclonal VEGI-2052R unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rVEGI-1283 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 67-251) antibodyTNFSF15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal VEGI-1283 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) antibodyTNFSF15 适用: 人 IHC (p) 宿主: 兔 Monoclonal VEGI-2052R unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) antibodyTNFSF15 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) antibodyTNFSF15 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL (1)
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TL1A antibody to be titered up or down for optimal performance.1. Staining of FFPE tissue requires boiling sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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别名
- TL1A
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背景
- TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer.
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基因ID
- 9966
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UniProt
- O95150
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途径
- Positive Regulation of Endopeptidase Activity, Autophagy
抗原
-
