Retinoblastoma Protein (Rb) 抗体
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Quick Overview for Retinoblastoma Protein (Rb) 抗体 (ABIN6252811)
抗原
See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human recombinant protein was used as the immunogen for this Rb antibody.
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亚型
- IgG1 kappa
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应用备注
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WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg protein lysate
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Titering of the Rb antibody may be required for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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别名
- Retinoblastoma / Rb
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背景
- Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
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基因ID
- 5925
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UniProt
- P06400
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途径
- Mitotic G1-G1/S Phases
抗原
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