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Retinoblastoma Protein (Rb) 抗体

This anti-Retinoblastoma Protein (Rb) antibody is a 小鼠 单克隆 antibody detecting Retinoblastoma Protein (Rb) in WB, IP 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6252811
发货至: 中国

Quick Overview for Retinoblastoma Protein (Rb) 抗体 (ABIN6252811)

抗原

See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

适用

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人, 小鼠

宿主

  • 124
  • 24
小鼠

克隆类型

  • 122
  • 26
单克隆

标记

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This Retinoblastoma Protein (Rb) antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1-1754
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    A human recombinant protein was used as the immunogen for this Rb antibody.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 0.5-1 μg/mL

    IP: 1-2 μg/500 μg protein lysate

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    Titering of the Rb antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

    别名

    Retinoblastoma / Rb

    背景

    Recognizes a 105  kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

    基因ID

    5925

    UniProt

    P06400

    途径

    Mitotic G1-G1/S Phases
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