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Retinoblastoma Protein (Rb) 抗体 (pSer788)

Name: Retinoblastoma Protein (Rb) 抗体 (pSer788)
SKU: ABIN3032467
Availability: OutOfStock

Rb Protein 适用: 人 ELISA, IHC, DB 宿主: 兔 Polyclonal unconjugated

IHC analysis of FFPE human hepatocarcinoma tissue stained with the phospho-Rb antibody.

IHC

Dot blot analysis of phospho-Rb antibody.

3 images

产品编号 ABIN3032467

发货至: 中国

Datasheet as PDF

抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
抗原表位
15

14

14

14

13

9

9

8

8

7

7

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer788
适用
174

71

56

8

8

7

7

5

3

3

3

2

1

1

1
人
宿主
151

24
兔
Compatible Secondaries
克隆类型
149

26
多克隆
标记
85

17

10

9

9

9

6

6

6

6

6

6
This Retinoblastoma Protein (Rb) antibody is un-conjugated
应用范围
89

88

84

27

26

15

14

9

2
ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

纯化方法

Antigen affinity purified

免疫原

This phospho-Rb antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS788 of human Rb.

亚型

Ig Fraction

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anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein 适用: 人 ELISA, IHC, IF, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibody
Rb Protein 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibody
Rb Protein 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 172C1094 unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibody
Rb Protein 适用: 人 ELISA, IHC, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibody
Rb Protein 适用: 人 ELISA, IHC, DB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) antibody
Rb Protein 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7E4B8 unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibody
Rb Protein 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Pig, 马, Bat WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibody
Rb Protein 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibody
Rb Protein 适用: 人, Cow, 犬, Pig, Bat, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Titration of the phospho-Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,IHC (Paraffin): 1:50-1:100

限制

仅限研究用
状态

Liquid

缓冲液

In 1X PBS, pH 7.4, with 0.09 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot the phospho-Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

别名

Retinoblastoma / Rb (Rb Protein 产品)

背景

RB1 likely acts as a regulator of other genes. It forms a complex with adenovirus E1A and with SV40 large T antigen, acts as a tumor suppressor, and may bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. RB1 is a potent inhibitor of E2F-mediated trans-activation, and also recruits and targets histone methyltransferase SUV39H1 leading to epigenetic transcriptional repression. This protein inhibits the intrinsic kinase activity of TAF1. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB), a congenital malignant tumor that arises from the nuclear layers of the retina. Defects in RB1 are also a cause of bladder cancer and osteogenic sarcoma.

UniProt

P06400

途径

Mitotic G1-G1/S Phases