TIA1 抗体 (AA 279-380)
Quick Overview for TIA1 抗体 (AA 279-380) (ABIN6252793)
抗原
See all TIA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 279-380
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human partial recombinant protein (amino acids 279-380) was used as the immunogen for this TIA-1 antibody.
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亚型
- IgG2b
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibody
TIA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A3B9 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-193) antibodyTIA1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2A10B12 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyVerified TIA1 适用: 人 WB, IF, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-214) antibodyTIA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (C-Term) antibodyTIA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIA-1 antibody to be titered up or down for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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别名
- TIA-1
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背景
- T-Cell Intracellular Antigen-1 is a cytoplasmic granule-associated protein expressed in lymphocytes processing cytolytic potential. It is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. TIA-1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.
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基因ID
- 7072
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UniProt
- P31483
抗原
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