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Nkx2-2 抗体

This 兔 多克隆 anti-Nkx2-2 antibody specifically detects Nkx2-2 in IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6252568
发货至: 中国
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Room 801-803
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Quick Overview for Nkx2-2 抗体 (ABIN6252568)

抗原

See all Nkx2-2 抗体
Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Nkx2-2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

    亚型

    IgG
  • 应用备注

    Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml

    IF: 1-2 μg/mL

    IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

    Titering of the NKX2.2 antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

    别名

    NKX2.2

    背景

    Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

    基因ID

    4821

    UniProt

    O95096

    途径

    Dopaminergic Neurogenesis
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