Nkx2-2 抗体
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北京 101111
Quick Overview for Nkx2-2 抗体 (ABIN6252568)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein A affinity chromatography
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免疫原
- A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
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亚型
- IgG
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应用备注
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Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT
Titering of the NKX2.2 antibody may be required for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- NKX2.2
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背景
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
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基因ID
- 4821
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UniProt
- O95096
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途径
- Dopaminergic Neurogenesis
抗原
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