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Integrin beta 2 抗体

This anti-Integrin beta 2 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 2 in FACS, WB, IF 和 Func. Suitable for 人.
产品编号 ABIN6252194
发货至: 中国

Quick Overview for Integrin beta 2 抗体 (ABIN6252194)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

68-5A5
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Stimulated human leukocytes were used as the immunogen for the CD18 antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Functional Activity (Order SAF formulation)

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the CD18 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18

    背景

    It recognizes a transmembrane glycoprotein of 95  kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This mAb blocks these cellular interactions.

    基因ID

    3689

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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