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NADPH Oxidase 4 抗体

This anti-NADPH Oxidase 4 antibody is a 小鼠 单克隆 antibody detecting NADPH Oxidase 4 in WB, ELISA, FACS 和 IF. Suitable for 人.
产品编号 ABIN6252095
发货至: 中国

Quick Overview for NADPH Oxidase 4 抗体 (ABIN6252095)

抗原

See all NADPH Oxidase 4 (NOX4) 抗体
NADPH Oxidase 4 (NOX4)

适用

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宿主

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小鼠

克隆类型

  • 85
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单克隆

标记

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This NADPH Oxidase 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

NOX4-1245
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Human recombinant protein was used as the immunogen for this NOX4 antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

    IF: 1-2 μg/mL

    ELISA: suitable, order BSA-free formulation for coating

    WB: 0.5-1 μg/mL

    Titering of the NOX4 antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    NADPH Oxidase 4 (NOX4)

    别名

    NOX4

    背景

    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

    基因ID

    4821

    UniProt

    Q9NPH5

    途径

    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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