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JUP 抗体

JUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat WB, IF, IP 宿主: 小鼠 Monoclonal 15F11 unconjugated
产品编号 ABIN6252060
发货至: 中国
  • 抗原 See all JUP 抗体
    JUP (Junction Plakoglobin (JUP))
    适用
    • 147
    • 59
    • 51
    • 22
    • 16
    • 13
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat
    宿主
    • 91
    • 55
    • 2
    • 1
    小鼠
    克隆类型
    • 83
    • 66
    单克隆
    标记
    • 65
    • 11
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This JUP antibody is un-conjugated
    应用范围
    • 109
    • 52
    • 36
    • 36
    • 32
    • 27
    • 26
    • 21
    • 18
    • 9
    • 9
    • 4
    • 3
    • 1
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
    克隆位点
    15F11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product JUP Primary Antibody
  • 应用备注
    Immunofluorescence: 1-2 μg/mL

    WB: 0.5-1 μg/mL

    Immunoprecipitation: suitable

    The stated application concentrations are suggested starting amounts. Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    JUP (Junction Plakoglobin (JUP))
    别名
    Gamma Catenin (JUP 产品)
    别名
    ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
    背景
    Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]
    基因ID
    3728
    UniProt
    P14923
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location
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