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Growth Hormone 1 抗体 (AA 58-187)

This anti-Growth Hormone 1 antibody is a 小鼠 单克隆 antibody detecting Growth Hormone 1 in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN6252006
发货至: 中国

Quick Overview for Growth Hormone 1 抗体 (AA 58-187) (ABIN6252006)

抗原

See all Growth Hormone 1 (GH1) 抗体
Growth Hormone 1 (GH1)

适用

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宿主

  • 86
  • 80
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 98
  • 72
单克隆

标记

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This Growth Hormone 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GH-1371
  • 抗原表位

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    AA 58-187

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 58-187 from the human protein were used as the immunogen for this Growth Hormone antibody.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: 0.5-1 μg/10^6 cells

    IF: 1-2 μg/mL

    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    Titration of the Growth Hormone antibody may be needed for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Growth Hormone 1 (GH1)

    别名

    Growth Hormone

    背景

    Growth hormone (GH), also known as somatotropin (or as human growth hormone [hGH or HGH] in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland.

    GH is a stress hormone that raises the concentration of glucose and free fatty acids. It also stimulates production of IGF-1.

    The major isoform of the human growth hormone is a protein of 191 amino acids and a molecular weight of 22,124 daltons. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. [Wiki]

    基因ID

    2688

    UniProt

    P01241

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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