Calnexin 抗体
Quick Overview for Calnexin 抗体 (ABIN6251945)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Does not react with rat
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
-
WB: 0.5-1 μg/mL
Flow Cytometry: 0.5-1 μg/10^6 cells
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Titering of the Calnexin antibody may be required for optimal performance. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
-
- Calnexin (CANX)
-
别名
- Calnexin
-
背景
- It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
-
途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
-