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Calnexin 抗体

This anti-Calnexin antibody is a 小鼠 单克隆 antibody detecting Calnexin in WB, IF, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN6251945
发货至: 中国

Quick Overview for Calnexin 抗体 (ABIN6251945)

抗原

See all Calnexin (CANX) 抗体
Calnexin (CANX)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Calnexin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CANX-1541
  • 特异性

    Does not react with rat

    纯化方法

    Protein G affinity chromatography

    免疫原

    A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

    亚型

    IgG2b kappa
  • 应用备注

    WB: 0.5-1 μg/mL

    Flow Cytometry: 0.5-1 μg/10^6 cells

    Immunofluorescence: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

    Titering of the Calnexin antibody may be required for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Calnexin (CANX)

    别名

    Calnexin

    背景

    It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

    途径

    MAPK Pathway, Thyroid Hormone Synthesis
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