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S100A8 抗体 (N-Term)

This anti-S100A8 antibody is a 小鼠 单克隆 antibody detecting S100A8 in WB. Suitable for 人.
产品编号 ABIN6251942
发货至: 中国

Quick Overview for S100A8 抗体 (N-Term) (ABIN6251942)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This S100A8 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

SA6279
  • 抗原表位

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    N-Term

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant protein fragment from the N-terminal region of human S100A8 was used as the immunogen for this antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Western blot: 2-4 μg/mL

    Provided assay concentrations are suggestions only, S100A8 antibody titration may be required for optimal results.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    S100A8

    背景

    The S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.

    基因ID

    6279

    UniProt

    P05109

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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