CAMK2B 抗体 (AA 1-503)
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北京 101111
Quick Overview for CAMK2B 抗体 (AA 1-503) (ABIN6244287)
抗原
See all CAMK2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-503
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This CAMK2 beta antibody is generated from a mouse immunized with a recombinant protein between 1-503 amino acids from human CAMK2 beta.
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亚型
- IgG1
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anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-100) antibody
CAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) antibodyCAMK2B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr286) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 101-200) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-504) antibodyCAMK2B 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-503) antibodyCAMK2B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 1-504) antibodyCAMK2B 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal S11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr287) antibodyCAMK2B 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (AA 405-502) antibodyCAMK2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6D6 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B) (pThr286), (Thr287) antibodyCAMK2B 适用: 大鼠 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 22B1 unconjugated
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应用备注
- WB: 1:2000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
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别名
- CAMK2 beta
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背景
- Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
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分子量
- 72678
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UniProt
- Q13554
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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