RIPK3 抗体
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北京 101111
Quick Overview for RIPK3 抗体 (ABIN6243991)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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预测反应
- H
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3.
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亚型
- IgG1 kappa
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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别名
- RIPK3
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背景
- Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
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分子量
- 56887
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UniProt
- Q9Y572
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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