IFT57 抗体 (AA 159-193)
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北京 101111
Quick Overview for IFT57 抗体 (AA 159-193) (ABIN6243690)
抗原
See all IFT57 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 159-193
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IFT57 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-193 amino acids from the Central region of human IFT57.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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别名
- IFT57
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背景
- Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
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分子量
- 49108
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UniProt
- Q9NWB7
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途径
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
抗原
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