FANCD2 抗体 (AA 893-927)
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北京 101111
Quick Overview for FANCD2 抗体 (AA 893-927) (ABIN6243659)
抗原
See all FANCD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 893-927
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FANCD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 893-927 amino acids from the Central region of human FANCD2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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别名
- FANCD2
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背景
- Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
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分子量
- 164128
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UniProt
- Q9BXW9
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途径
- DNA Damage Repair
抗原
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