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FANCD2 抗体 (AA 893-927)

This anti-FANCD2 antibody is a 兔 多克隆 antibody detecting FANCD2 in WB. Suitable for 人.
产品编号 ABIN6243659
发货至: 中国

Quick Overview for FANCD2 抗体 (AA 893-927) (ABIN6243659)

抗原

See all FANCD2 抗体
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

适用

  • 70
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宿主

  • 70
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克隆类型

  • 60
  • 11
多克隆

标记

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This FANCD2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB49367
  • 抗原表位

    • 16
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    AA 893-927

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FANCD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 893-927 amino acids from the Central region of human FANCD2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    别名

    FANCD2

    背景

    Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.

    分子量

    164128

    UniProt

    Q9BXW9

    途径

    DNA Damage Repair
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