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FZD10 抗体 (N-Term)

This anti-FZD10 antibody is a 兔 多克隆 antibody detecting FZD10 in WB. Suitable for 小鼠.
产品编号 ABIN6243622
发货至: 中国

Quick Overview for FZD10 抗体 (N-Term) (ABIN6243622)

抗原

See all FZD10 抗体
FZD10 (Frizzled Family Receptor 10 (FZD10))

适用

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小鼠

宿主

  • 51
  • 2

克隆类型

  • 49
  • 2
  • 1
多克隆

标记

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  • 1
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  • 1
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  • 1
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  • 1
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This FZD10 antibody is un-conjugated

应用范围

  • 37
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Western Blotting (WB)

克隆位点

RB52084
  • 抗原表位

    • 15
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 177-212, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FZD10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 177-212 amino acids from the N-terminal region of human FZD10.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    FZD10 (Frizzled Family Receptor 10 (FZD10))

    别名

    FZD10

    背景

    Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    分子量

    65336

    UniProt

    Q9ULW2

    途径

    WNT signaling
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