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DDR1 抗体 (AA 396-430)

This anti-DDR1 antibody is a 兔 多克隆 antibody detecting DDR1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN6243407
发货至: 中国

Quick Overview for DDR1 抗体 (AA 396-430) (ABIN6243407)

抗原

See all DDR1 抗体
DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

适用

  • 87
  • 35
  • 35
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 90
  • 11
  • 3

克隆类型

  • 88
  • 13
  • 2
多克隆

标记

  • 53
  • 6
  • 4
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  • 2
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  • 2
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  • 2
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  • 2
  • 2
  • 2
  • 2
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  • 1
This DDR1 antibody is un-conjugated

应用范围

  • 78
  • 41
  • 26
  • 26
  • 23
  • 14
  • 13
  • 7
  • 6
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB50593
  • 抗原表位

    • 25
    • 15
    • 7
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 396-430

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Ddr1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 396-430 amino acids from the Central region of human Mouse Ddr1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

    别名

    Ddr1

    背景

    Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.

    分子量

    101161

    UniProt

    Q03146

    途径

    RTK signaling, Smooth Muscle Cell Migration
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