This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This mouse Bmi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-268 amino acids from the C-terminal region of mouse Bmi1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
抗原
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
别名
Bmi1
背景
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).