LRRK2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for LRRK2 抗体 (C-Term) (ABIN6243251)
抗原
See all LRRK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 2171-2207, C-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This LRRK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2171-2207 amino acids from the C-terminal region of human LRRK2.
-
亚型
- Ig Fraction
-
-
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibody
LRRK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibodyLRRK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7199 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB07209 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7207 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 133AT1218 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 133AT720 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 133AT720 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (C-Term) antibodyLRRK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000. IHC: 1:25. FC: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
-
别名
- LRRK2
-
背景
- Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH , and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (,CNS),. Phosphorylates PRDX3. May also have GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
-
分子量
- 286103
-
UniProt
- Q5S007
-
途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
抗原
-
