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LRRK2 抗体 (C-Term)

LRRK2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 133AT1218 unconjugated
产品编号 ABIN387804
发货至: 中国
  • 抗原 See all LRRK2 抗体
    LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
    抗原表位
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 20
    • 7
    • 1
    人, 小鼠
    宿主
    • 18
    • 2
    小鼠
    克隆类型
    • 17
    • 3
    单克隆
    标记
    • 17
    • 1
    • 1
    • 1
    This LRRK2 antibody is un-conjugated
    应用范围
    请咨询
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This PARK8 (LRRK2) antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.
    克隆位点
    133AT1218
    亚型
    IgG1
    Top Product
    Discover our top product LRRK2 Primary Antibody
  • 应用备注
    IHC: 1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Ortiz-Ortiz, Morán, Ruiz-Mesa, Niso-Santano, Bravo-SanPedro, Gómez-Sánchez, González-Polo, Fuentes: "Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells." in: Neuroscience letters, Vol. 468, Issue 2, pp. 120-4, (2009) (PubMed).

    Biskup, Moore, Rea, Lorenz-Deperieux, Coombes, Dawson, Dawson, West: "Dynamic and redundant regulation of LRRK2 and LRRK1 expression." in: BMC neuroscience, Vol. 8, pp. 102, (2008) (PubMed).

  • 抗原
    LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
    别名
    PARK8 (LRRK2) (LRRK2 产品)
    别名
    LRRK2 antibody, AURA17 antibody, DARDARIN antibody, PARK8 antibody, RIPK7 antibody, ROCO2 antibody, 4921513O20Rik antibody, 9330188B09Rik antibody, AW561911 antibody, D630001M17Rik antibody, Gm927 antibody, cI-46 antibody, leucine-rich repeat kinase 2 antibody, leucine rich repeat kinase 2 antibody, lrrk2 antibody, LRRK2 antibody, Lrrk2 antibody
    背景
    This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
    分子量
    286103
    基因ID
    120892
    NCBI登录号
    NP_940980
    UniProt
    Q5S007
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
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