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- 抗原 See all LRRK2 抗体
- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRRK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antigen affinity purified
- 免疫原
- This LRRK2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2171-2207 amino acids from the C-terminal region of human LRRK2.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LRRK2 Primary Antibody
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anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 2355-2527) antibody
LRRK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibodyLRRK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 1479-1729) antibodyLRRK2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 2171-2207), (C-Term) antibodyLRRK2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal RB50924 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 878-909) antibodyLRRK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7207 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 931-962) antibodyLRRK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7199 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 930-961) antibodyLRRK2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB07209 unconjugated
anti-Leucine-Rich Repeat Kinase 2 (LRRK2) (AA 2029-2275) antibodyLRRK2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the LRRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))
- 别名
- LRRK2 (LRRK2 产品)
- 别名
- LRRK2 antibody, AURA17 antibody, DARDARIN antibody, PARK8 antibody, RIPK7 antibody, ROCO2 antibody, 4921513O20Rik antibody, 9330188B09Rik antibody, AW561911 antibody, D630001M17Rik antibody, Gm927 antibody, cI-46 antibody, leucine-rich repeat kinase 2 antibody, leucine rich repeat kinase 2 antibody, lrrk2 antibody, LRRK2 antibody, Lrrk2 antibody
- 背景
- Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH , and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (,CNS),. Phosphorylates PRDX3. May also have GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
- UniProt
- Q5S007
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
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