MAPK12 抗体 (AA 319-353)
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Quick Overview for MAPK12 抗体 (AA 319-353) (ABIN6243201)
抗原
See all MAPK12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 319-353
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This (DANRE) mapk12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids of DANRE mapk12.
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亚型
- IgG
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- MAPK12 (Mitogen-Activated Protein Kinase 12 (MAPK12))
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别名
- mapk12
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背景
- Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity).
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分子量
- 41971
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UniProt
- O42376
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C, BCR Signaling, S100 Proteins
抗原
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