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SMAD2 抗体 (AA 198-232)

This anti-SMAD2 antibody is a 兔 多克隆 antibody detecting SMAD2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6242555
发货至: 中国

Quick Overview for SMAD2 抗体 (AA 198-232) (ABIN6242555)

抗原

See all SMAD2 抗体
SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 231
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多克隆

标记

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This SMAD2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB51534
  • 抗原表位

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    AA 198-232

    预测反应

    B, C, Pig

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This mouse Smad2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-232 amino acids from the Central region of mouse Smad2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

    别名

    Smad2

    背景

    Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).

    分子量

    52266

    UniProt

    Q62432

    途径

    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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