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Nicastrin 抗体 (AA 99-133)

The 兔 多克隆 anti-Nicastrin antibody (Clone RB53031) (ABIN6242494) specifically detects Nicastrin in WB. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN6242494
发货至: 中国
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Quick Overview for Nicastrin 抗体 (AA 99-133) (ABIN6242494)

抗原

See all Nicastrin (NCSTN) 抗体
Nicastrin (NCSTN)

适用

  • 50
  • 34
  • 22
  • 5
  • 5
  • 4
  • 1
  • 1
人, 大鼠

宿主

  • 65
  • 2

克隆类型

  • 46
  • 21
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Nicastrin antibody is un-conjugated

应用范围

  • 52
  • 17
  • 15
  • 13
  • 13
  • 10
  • 7
  • 6
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB53031
  • 抗原表位

    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 99-133

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NCSTN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from human NCSTN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:8000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Nicastrin (NCSTN)

    别名

    NCSTN

    背景

    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

    分子量

    78411

    UniProt

    Q92542

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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