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MBD2 抗体 (AA 10-228)

This 小鼠 单克隆 anti-MBD2 antibody (Clone 1812CT625-9-45) specifically detects MBD2 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6242434
发货至: 中国
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Quick Overview for MBD2 抗体 (AA 10-228) (ABIN6242434)

抗原

See all MBD2 抗体
MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

适用

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宿主

  • 64
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小鼠

克隆类型

  • 42
  • 24
单克隆

标记

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This MBD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1812CT625-9-45
  • 抗原表位

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    AA 10-228

    纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 1:2000. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

    别名

    MBD2

    背景

    Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.

    分子量

    43255

    UniProt

    Q9UBB5

    途径

    Chromatin Binding
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