This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This FKBP1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the Central region of human FKBP1A.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
有效期
6 months
抗原
FKBP1A
(FK506 Binding Protein 1A, 12kDa (FKBP1A))
别名
FKBP1A
背景
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.