EPAS1 抗体 (C-Term)
Quick Overview for EPAS1 抗体 (C-Term) (ABIN6242310)
抗原
See all EPAS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 713-747, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Epas1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 713-747 amino acids from the C-terminal region of Mouse Epas1.
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亚型
- Ig Fraction
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anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 339-541) antibody
EPAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 21-336) antibodyEPAS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (Ser343) antibodyEPAS1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 680-870) antibodyEPAS1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1H3E12 unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (C-Term) antibodyEPAS1 适用: 人, 大鼠, 小鼠, 鱼 WB, IHC, ELISA, IP, ICC, FACS, IF, ChIP, GS 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 28-347) antibodyEPAS1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 588-870) antibodyEPAS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) antibodyEPAS1 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 535-631) antibodyEPAS1 适用: 人, 大鼠, 小鼠, Hamster WB, IHC, ELISA, IP, ICC, FACS, IF, ChIP 宿主: 小鼠 Monoclonal ep190b unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 1-130) antibodyEPAS1 适用: 人, 大鼠, 小鼠, 猴, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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别名
- Epas1
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背景
- Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
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分子量
- 96712
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UniProt
- P97481
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
抗原
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