DMBT1 抗体 (AA 2160-2192)
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北京 101111
Quick Overview for DMBT1 抗体 (AA 2160-2192) (ABIN6242287)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2160-2192
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DMBT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2160-2192 amino acids from human DMBT1.
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亚型
- Ig Fraction
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anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibody
DMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 1701-1785) antibodyDMBT1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2008-2413) antibodyDMBT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) antibodyDMBT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibodyDMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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别名
- DMBT1
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背景
- May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly- sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.
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分子量
- 260735
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UniProt
- Q9UGM3
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途径
- Activation of Innate immune Response
抗原
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