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Cyclin D3 抗体 (N-Term)

This anti-Cyclin D3 antibody is a 兔 多克隆 antibody detecting Cyclin D3 in WB. Suitable for 大鼠.
产品编号 ABIN6242272
发货至: 中国

Quick Overview for Cyclin D3 抗体 (N-Term) (ABIN6242272)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

适用

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大鼠

宿主

  • 87
  • 15

克隆类型

  • 79
  • 23
多克隆

标记

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This Cyclin D3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB43404
  • 抗原表位

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    AA 33-66, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This rat Ccnd3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-66 amino acids from the N-terminal region of rat Ccnd3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500-1:1000. WB: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Cyclin D3 (CCND3)

    别名

    Ccnd3

    背景

    Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

    分子量

    32434

    UniProt

    P48961

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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