电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

H2AFX 抗体 (pSer139)

This anti-H2AFX antibody is a 小鼠 单克隆 antibody detecting H2AFX in WB 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6241012
发货至: 中国

Quick Overview for H2AFX 抗体 (pSer139) (ABIN6241012)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

适用

  • 170
  • 82
  • 61
  • 25
  • 25
  • 19
  • 17
  • 11
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 156
  • 17
  • 2
小鼠

克隆类型

  • 127
  • 48
单克隆

标记

  • 119
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This H2AFX antibody is un-conjugated

应用范围

  • 137
  • 57
  • 49
  • 44
  • 33
  • 28
  • 27
  • 21
  • 16
  • 15
  • 8
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC)
  • 抗原表位

    • 35
    • 20
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139

    免疫原

    Recombinant Protein
  • 应用备注

    WB: 1:2000. ICC: 1:400

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C,-20 °C
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    Histone H2A.X

    背景

    Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.

    UniProt

    P16104

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
You are here:
Chat with us!