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LIG3 抗体

This anti-LIG3 antibody is a 兔 多克隆 antibody detecting LIG3 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN3022649
发货至: 中国

Quick Overview for LIG3 抗体 (ABIN3022649)

抗原

See all LIG3 抗体
LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

适用

  • 44
  • 16
  • 16
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 42
  • 2

克隆类型

  • 43
  • 1
多克隆

标记

  • 28
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LIG3 antibody is un-conjugated

应用范围

  • 30
  • 16
  • 8
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human LIG3

    亚型

    IgG
  • 应用备注

    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C/-80 °C
  • Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

    Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).

  • 抗原

    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

    别名

    LIG3

    背景

    This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
    Synonyms: LIG2, LIG3

    基因ID

    3980

    UniProt

    P49916

    途径

    DNA Damage Repair
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