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MUTYH 抗体

This anti-MUTYH antibody is a 兔 多克隆 antibody detecting MUTYH in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3022243
发货至: 中国

Quick Overview for MUTYH 抗体 (ABIN3022243)

抗原

See all MUTYH 抗体
MUTYH (MutY Homolog (E. Coli) (MUTYH))

适用

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人, 小鼠, 大鼠

宿主

  • 48
  • 5
  • 3

克隆类型

  • 51
  • 5
多克隆

标记

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This MUTYH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human MUTYH

    亚型

    IgG
  • 应用备注

    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C/-80 °C
  • 抗原

    MUTYH (MutY Homolog (E. Coli) (MUTYH))

    别名

    MUTYH

    背景

    Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches. Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria. MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage. Research studies have shown that mutations in the corresponding MYH gene are associated with human gastric and colorectal cancers.
    Synonyms: MGC4416, MYH

    基因ID

    4595

    UniProt

    Q9UIF7

    途径

    DNA Damage Repair
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