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Recombinant Tyrosinase-Related Protein 1 抗体 (CF®647)

This anti-Tyrosinase-Related Protein 1 antibody is a 兔 单克隆 antibody detecting Tyrosinase-Related Protein 1 in IHC, IF 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN6191368
发货至: 中国

Quick Overview for Recombinant Tyrosinase-Related Protein 1 抗体 (CF®647) (ABIN6191368)

抗原

See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
Tyrosinase-Related Protein 1 (TYRP1)

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

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克隆类型

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单克隆

标记

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This Tyrosinase-Related Protein 1 antibody is conjugated to CF®647

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

TYRP1-1564R
  • 原理

    Recombinant Rabbit Monoclonal anti-Tyrosinase Related Protein-1 (TYRP1/1564R), CF647 Conjugate

    产品特性

    This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length TYRP1 protein

    亚型

    IgG kappa
  • 应用备注

    Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunohistology (formalin) 5-10 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells or Melanoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    Tyrosinase-Related Protein 1 (TYRP1)

    别名

    Tyrosinase Related Protein-1

    分子量

    75 kDa

    基因ID

    7306, 270279

    UniProt

    P17643
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