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MUC5AC 抗体 (CF®640R)

This anti-MUC5AC antibody is a 小鼠 单克隆 antibody detecting MUC5AC in IF, FACS 和 IHC (f). Suitable for 人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig 和 Hedgehog.
产品编号 ABIN6186120
发货至: 中国

Quick Overview for MUC5AC 抗体 (CF®640R) (ABIN6186120)

抗原

See all MUC5AC 抗体
MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

适用

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人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig, Hedgehog

宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC5AC antibody is conjugated to CF®640R

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

45M1
  • 原理

    Mouse Monoclonal anti-Mucin 5AC (MUC5AC) (45M1), CF640R Conjugate

    产品特性

    This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. TheA,  epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistology formalin-fixed 1-2 μg/mL
    • Does not react with cow, others not known
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 1-2 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells in 0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Stomach

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

    别名

    Mucin 5AC (MUC5AC)

    背景

    Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)

    分子量

    >1,000 kDa

    基因ID

    4586, 534332

    UniProt

    P98088
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