CD70 抗体 (CF®405S)
Quick Overview for CD70 抗体 (CF®405S) (ABIN6185090)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CD70 (BU69), CF405S Conjugate
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产品特性
- This antibody recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toinhibit T cell proliferation induced by dendritic cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Human WM-1 (Waldenstrom s macroglobulinemia) cell line
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亚型
- IgG1 kappa
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anti-CD70 Molecule (CD70) (AA 39-193) antibody
CD70 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 unconjugated
anti-CD70 Molecule (CD70) antibody (PE)CD70 适用: 人 FACS 宿主: 小鼠 Monoclonal Ki-24 PE
anti-CD70 Molecule (CD70) (AA 47-191) antibodyCD70 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 1-193) antibodyCD70 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibodyCD70 适用: 人 WB, FACS 宿主: 兔 Monoclonal unconjugated
anti-CD70 Molecule (CD70) (AA 72-101) antibodyCD70 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) (AA 64-192) antibodyCD70 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD70 Molecule (CD70) antibody (PerCP-Cy5.5)CD70 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal FR70 PerCP-Cy5.5
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应用备注
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Immunohistology (frozen) 0.5-1 μg/mL
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunoprecipitation 0.5-1 μg/500 μg protein lysate
- ELISA For coating, order Ab without BSA
- Inhibits T cell proliferation induced by dendritic cells
- Optimal dilution for a specific application should be determined by user
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说明
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Raji cells. Lymph node or tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
- CD27 ligand (CD27L), CD27LG, Ki24, Surface antigen CD70, Tumor necrosis factor (ligand) superfamily, member 7 (TNFSF7)
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分子量
- ~30 kDa
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基因ID
- 970
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UniProt
- P32970
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途径
- Cancer Immune Checkpoints
抗原
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