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GJB1 抗体 (CF®594)

This anti-GJB1 antibody is a 大鼠 单克隆 antibody detecting GJB1 in WB, IF, FACS 和 IHC (fro). Suitable for 大鼠 和 小鼠.
产品编号 ABIN6178502
发货至: 中国

Quick Overview for GJB1 抗体 (CF®594) (ABIN6178502)

抗原

See all GJB1 抗体
GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

适用

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大鼠, 小鼠

宿主

  • 55
  • 27
  • 11
大鼠

克隆类型

  • 54
  • 39
单克隆

标记

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This GJB1 antibody is conjugated to CF®594

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

R5-21C
  • 原理

    Rat Monoclonal anti-Connexin-32 (R5.21C), CF594 Conjugate

    产品特性

    This antibody recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Mouse liver DOC-JR-plasma membranes

    亚型

    IgG2a
  • 应用备注

    Immunohistology (frozen) 0.5-1 μg/mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells
    • Optimal dilution for a specific application should be determined by user

    说明

    MCF-7 Cells. Pancreas, Liver, Kidney, Stomach or Tonsil

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

    别名

    Connexin-32

    背景

    Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28  kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1

    分子量

    27-32 kDa

    基因ID

    14618

    途径

    Cell-Cell Junction Organization
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