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GJB1 抗体 (CF®405S)

GJB1 适用: 人, 大鼠, 小鼠 WB, IF, IHC, FACS 宿主: 小鼠 Monoclonal GJB1-1753 CF®405S
产品编号 ABIN6178402
发货至: 中国
  • 抗原 See all GJB1 抗体
    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 50
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    小鼠
    克隆类型
    • 50
    • 34
    单克隆
    标记
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    This GJB1 antibody is conjugated to CF®405S
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-Connexin-32 (GJB1/1753), CF405S Conjugate
    产品特性
    This Ab recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human GJB1 protein
    克隆位点
    GJB1-1753
    亚型
    IgG
    Top Product
    Discover our top product GJB1 Primary Antibody
  • 应用备注
    Immunohistology (formalin) 1-2 μg/mL
    • Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    MCF-7 Cells. Liver, Kidney, Stomach or Tonsil

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
    别名
    Connexin-32 (GJB1 产品)
    别名
    GJIC antibody, cmtx antibody, cmtx1 antibody, connexin-30 antibody, connexin32 antibody, cx30 antibody, cx32 antibody, gja1 antibody, CX32 antibody, GJB1 antibody, AI118175 antibody, Cnx32 antibody, Cx32 antibody, Gjb-1 antibody, CMTX antibody, CMTX1 antibody, gjb1-a antibody, gap junction protein beta 1 antibody, connexin 32 antibody, probable serine/threonine-protein kinase CST antibody, gap junction protein, beta 1 antibody, gap junction protein beta 1 L homeolog antibody, gjb1 antibody, CX32 antibody, LOC9303136 antibody, GJB1 antibody, Gjb1 antibody, gjb1.L antibody
    背景
    Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28  kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1
    分子量
    27-32 kDa
    基因ID
    2705, 333303
    UniProt
    P08034
    途径
    Cell-Cell Junction Organization
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