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Integrin beta 2 抗体 (Biotin)

This anti-Integrin beta 2 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 2 in FACS 和 IF. Suitable for 人.
产品编号 ABIN6169045
发货至: 中国
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中国
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Integrin beta 2 抗体 (Biotin) (ABIN6169045)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

68-5A5
  • 原理

    Mouse Monoclonal anti-CD18 (68-5A5), Biotin Conjugate

    产品特性

    This antibody recognizes a transmembrane glycoprotein of 95 kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Stimulated human leukocytes

    亚型

    IgG2a kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Lymphocytes, granulocytes, and macrophages in tonsil or lymph node.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18

    分子量

    95 kDa

    基因ID

    3689, 375957

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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