IGF2R 抗体 (PE)
Our Local Distributor
北京 101111
Quick Overview for IGF2R 抗体 (PE) (ABIN616775)
抗原
See all IGF2R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10e6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
-
交叉反应 （详细）
- Species reactivity (tested):Human, Non-Human Primates
-
免疫原
- Recombinant Vaccinia virus encoding CD222
-
亚型
- IgG1
-
-
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody
IGF2R 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibodyIGF2R 适用: 人, Non-Human Primate WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-238 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 424-529) antibodyIGF2R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2327-2491) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibodyIGF2R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 160-311) antibodyIGF2R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F1G1 unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2441-2490) antibodyIGF2R 适用: 人, 小鼠, 大鼠 IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibodyKD Validated IGF2R 适用: 人 WB 宿主: 兔 Monoclonal 25GB6790 unconjugated Recombinant Antibody
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (FITC)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 FITC
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (PE)IGF2R 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-238 PE
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Dilute only prior to immediate use
-
储存条件
- 4 °C
-
储存方法
- Store the antibody (undiluted) at 2-8 °C prior to opening. DO NOT FREEZE! Store reagent in the dark. Use subdued lighting during handling and incubation of cells prior to analysis.
-
-
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
-
别名
- CD222 / IGF2R
-
背景
- CD222 (CIMPR, cation-independent mannose 6-phosphate receptor, IGF2 receptor) is a ubiquitously expressed 250 kDa transmembrane protein. No more than 10 % of CD222 is present on the cell surface where it serves as a multifunctional receptor. Intracellular (major) fraction of CD222 is involved in transport of newly synthesized lysosomal enzymes modified by mannose 6-phosphate from Golgi apparatus to lysosomes. The cell surface CD222 binds and internalizes exogeneous mannose 6-phosphate-containing ligands. Importantly, CD222 is crutial for internalization and degradation of insulin-like growth factor 2, thus controling cell growth. CD222 also complexes CD87 (urokinase-type plasminogen-activator receptor), plasminogen and latent TGF-beta, last but not least CD222 serves as a receptor for heparanase and even for Listeria.Synonyms: 300 kDa mannose 6-phosphate receptor, CI Man-6-P receptor, CI-MPR, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, Late Endosome Marker, M6P/IGF2 receptor, M6P/IGF2R, M6PR, MPR 300, Mannose 6 Phosphate Receptor (Cation independent)
-
基因ID
- 3482
-
NCBI登录号
- NP_000867
-
UniProt
- P11717
抗原
-
