JUP 抗体 (CF®647)
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北京 101111
Quick Overview for JUP 抗体 (CF®647) (ABIN6164937)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-Catenin, gamma (CTNG/1483), CF647 Conjugate
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产品特性
- This antibody recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (?, ?, ? and ?) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. ? T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. ? T-catenin binds to ? E-catenin as well as to ?-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for ?-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length gamma catenin protein
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亚型
- IgG1 kappa
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anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-745) antibodyJUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyVerified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 556-745) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-300) antibodyJUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1-10E05 unconjugated
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应用备注
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Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunohistology (formalin) 0.1-0.2 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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A431, T47D or MCF-7 cells. Skin
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- JUP (Junction Plakoglobin (JUP))
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别名
- Catenin, gamma
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背景
- ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB
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分子量
- 80-87 kDa
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基因ID
- 3728, 514174
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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