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JUP 抗体 (Biotin)

This anti-JUP antibody is a 小鼠 单克隆 antibody detecting JUP in WB, IF 和 FACS. Suitable for 人, 小鼠, 大鼠, 小鸡, Cow, 犬 和 Cat.
产品编号 ABIN6164920
发货至: 中国

Quick Overview for JUP 抗体 (Biotin) (ABIN6164920)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

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人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This JUP antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

15F11
  • 原理

    Mouse Monoclonal anti-Catenin, gamma (15F11), Biotin Conjugate

    产品特性

    This antibody recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (?, ?, ? and ?) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. ? T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. ? T-catenin binds to ? E-catenin as well as to ?-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for ?-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    full length chicken Catenin gamma protein|Recombinant

    亚型

    IgG1 kappa
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    A431, T47D or MCF-7 cells. Skin

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    Catenin, gamma

    背景

    ARVD12, Catenin (cadherin-associated protein), gamma 80  kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

    分子量

    80-87 kDa

    基因ID

    3728, 514174

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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