BIRC3 抗体
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北京 101111
Quick Overview for BIRC3 抗体 (ABIN615850)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to Baculoviral IAP Repeat-containing 3 (BIRC3). Predicted cross-reactivity based on amino acid sequence homology: bovine (84 %).
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Recombinant Human cIAP2. Genename: BIRC3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- 0.1 M Tris-glycine, pH 7.0 containing 10 % Glycerol and 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- IAP1 / BIRC3
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背景
- Apoptosis inhibitor 2 (API2) is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. API2 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. The names of API1 and API2 have been confusing. Suffice it to say that 'apoptosis inhibitor 2' is hiap-1 (inhibitor of apoptosis 1).Synonyms: API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, HIAP-1, IAP homolog C, Inhibitor of apoptosis protein 1, MIHC, RING finger protein 49, RNF49, TNFR2-TRAF-signaling complex protein 1, cIAP2
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基因ID
- 330
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NCBI登录号
- NP_001156
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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