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CEACAM5 抗体 (CF®405S)

This anti-CEACAM5 antibody is a 小鼠 单克隆 antibody detecting CEACAM5 in FACS 和 IF. Suitable for 人 和 猴.
产品编号 ABIN6151933
发货至: 中国

Quick Overview for CEACAM5 抗体 (CF®405S) (ABIN6151933)

抗原

See all CEACAM5 抗体
CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

适用

  • 143
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人, 猴

宿主

  • 93
  • 46
  • 6
小鼠

克隆类型

  • 106
  • 35
  • 2
单克隆

标记

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This CEACAM5 antibody is conjugated to CF®405S

应用范围

  • 84
  • 75
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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

C66-195
  • 原理

    Mouse Monoclonal anti-CD66 / CEA (C66/195), CF405S Conjugate

    产品特性

    This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human CEA protein

    亚型

    IgG1 kappa
  • 应用备注

    Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL

    说明

    MCF7 or 293T cells. Colon carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

    别名

    CD66 (CEA)

    背景

    Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)

    分子量

    80-200 kDa

    基因ID

    1048, 634, 709196

    UniProt

    P06731
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