TGFB1 抗体 (AA 30-280)
Quick Overview for TGFB1 抗体 (AA 30-280) (ABIN6149071)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-280
-
序列
- LSTCKTIDME LVKRKRIEAI RGQILSKLRL ASPPSQGEVP PGPLPEAVLA LYNSTRDRVA GESAEPEPEP EADYYAKEVT RVLMVETHNE IYDKFKQSTH SIYMFFNTSE LREAVPEPVL LSRAELRLLR LKLKVEQHVE LYQKYSNNSW RYLSNRLLAP SDSPEWLSFD VTGVVRQWLS RGGEIEGFRL SAHCSCDSRD NTLQVDINGF TTGRRGDLAT IHGMNRPFLL LMATPLERAQ HLQSSRHRRA L
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-280 of human TGFB1 (NP_000651.3).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
-
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 633-638, (2018) (PubMed).
: "Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated β-catenin stabilization in a toluene diisocyanate-induced ..." in: International immunopharmacology, Vol. 59, pp. 187-196, (2018) (PubMed).
: "Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling." in: International immunopharmacology, Vol. 55, pp. 1-8, (2018) (PubMed).
: "MiR-30c protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition in db/db mice." in: Aging cell, Vol. 16, Issue 2, pp. 387-400, (2017) (PubMed).
: "Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation." in: Oncotarget, Vol. 8, Issue 35, pp. 57981-57990, (2017) (PubMed).
: "Surfactant protein D regulates murine testicular immune milieu and sperm functions." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 77, Issue 3, (2017) (PubMed).
: "Effect of Trichostatin A on radiation induced epithelial-mesenchymal transition in A549 cells." in: Biochemical and biophysical research communications, Vol. 493, Issue 4, pp. 1534-1541, (2017) (PubMed).
: "
-
Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 633-638, (2018) (PubMed).
-
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
-
别名
- TGFB1
-
背景
- This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.,TGFB1,CED,DPD1,LAP,TGFB,TGFbeta,TGF-β,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Endocrine & Metabolism,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,Ligand,TGFB1
-
分子量
- 44 kDa
-
基因ID
- 7040
-
UniProt
- P01137
-
途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
-