TAB1 抗体 (AA 205-504)
Quick Overview for TAB1 抗体 (AA 205-504) (ABIN6148795)
抗原
See all TAB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 205-504
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序列
- VDHTTENEDE LFRLSQLGLD AGKIKQVGII CGQESTRRIG DYKVKYGYTD IDLLSAAKSK PIIAEPEIHG AQPLDGVTGF LVLMSEGLYK ALEAAHGPGQ ANQEIAAMID TEFAKQTSLD AVAQAVVDRV KRIHSDTFAS GGERARFCPR HEDMTLLVRN FGYPLGEMSQ PTPSPAPAAG GRVYPVSVPY SSAQSTSKTS VTLSLVMPSQ GQMVNGAHSA STLDEATPTL TNQSPTLTLQ STNTHTQSSS SSSDGGLFRS RPAHSLPPGE DGRVEPYVDF AEFYRLWSVD HGEQSVVTAP
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 205-504 of human TAB1 (NP_006107.1).
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 3-100) antibody
TAB1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 205-504) antibodyTAB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) antibodyTAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 601-712) antibodyTAB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) antibodyTAB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (C-Term) antibodyTAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) antibodyTAB1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) antibodyTAB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (AA 1-504) antibodyTAB1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) (N-Term) antibodyTAB1 适用: 人, 小鼠, 大鼠, Pig, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:10 - 1:100,IP,1:50 - 1:200
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说明
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HIGH QUALITY
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1))
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别名
- TAB1
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背景
- The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,TAB1,3'-Tab1,MAP3K7IP1,Signal Transduction,Kinase,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TAB1
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分子量
- 49 kDa/54 kDa
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基因ID
- 10454
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UniProt
- Q15750
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途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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