电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

RIPK3 抗体 (AA 1-120)

This anti-RIPK3 antibody is a 兔 多克隆 antibody detecting RIPK3 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN6146964
发货至: 中国

Quick Overview for RIPK3 抗体 (AA 1-120) (ABIN6146964)

抗原

See all RIPK3 抗体
RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

适用

  • 74
  • 42
  • 27
  • 6
  • 4
  • 4
  • 2
  • 1

宿主

  • 82
  • 15

克隆类型

  • 81
  • 16
多克隆

标记

  • 58
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RIPK3 antibody is un-conjugated

应用范围

  • 86
  • 53
  • 36
  • 19
  • 18
  • 14
  • 11
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120

    序列

    MSCVKLWPSG APAPLVSIEE LENQELVGKG GFGTVFRAQH RKWGYDVAVK IVNSKAISRE VKAMASLDNE FVLRLEGVIE KVNWDQDPKP ALVTKFMENG SLSGLLQSQC PRPWPLLCRL

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RIPK3 (NP_006862.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Qin, Yang, Huang, Du, Mai, Xiao, Lü: "Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia." in: Pharmacological research, Vol. 133, pp. 218-235, (2018) (PubMed).

    Mengying, Yiyue, Tong, Yue, Limpanont, Ping, Okanurak, Yanqi, Dekumyoy, Hongli, Watthanakulpanich, Zhongdao, Zhi, Zhiyue: "Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by Angiostrongylus cantonensis infection." in: Parasites & vectors, Vol. 10, Issue 1, pp. 611, (2018) (PubMed).

    Huang, Zheng, Wang, Chen, He, Zhang, Xu, Zhao, Shi, Wang, Zhu, Han: "The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process." in: Molecular and cellular biology, Vol. 37, Issue 5, (2017) (PubMed).

  • 抗原

    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

    别名

    RIPK3

    背景

    The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.,RIPK3,RIP3,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,RIPK3

    分子量

    25 kDa/27 kDa/56 kDa

    基因ID

    11035

    UniProt

    Q9Y572

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
You are here:
Chat with us!