RASGRF1 抗体 (AA 1-190)
Quick Overview for RASGRF1 抗体 (AA 1-190) (ABIN6146718)
抗原
See all RASGRF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-190
-
序列
- MQKGIRLNDG HVASLGLLAR KDGTRKGYLS KRSSDNTKWQ TKWFALLQNL LFYFESDSSS RPSGLYLLEG CVCDRAPSPK PALSAKEPLE KQHYFTVNFS HENQKALELR TEDAKDCDEW VAAIAHASYR TLATEHEALM QKYLHLLQIV ETEKTVAKQL RQQIEDGEIE IERLKAEITS LLKDNERIQS
-
交叉反应
- 小鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_001139120.1).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
-
别名
- RASGRF1
-
背景
- The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,RASGRF1,CDC25,CDC25L,GNRP,GRF1,GRF55,H-GRF55,PP13187,ras-GRF1,Signal Transduction,G protein signaling,Signal Transduction,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Actins,RASGRF1
-
分子量
- 55 kDa/143 kDa/145 kDa
-
基因ID
- 5923
-
UniProt
- Q13972
-
途径
- RTK signaling, Cell Division Cycle, M Phase
抗原
-