ADAM17 抗体 (AA 215-315)
Quick Overview for ADAM17 抗体 (AA 215-315) (ABIN614668)
抗原
See all ADAM17 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 215-315
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特异性
- This antibody reacts to A Disintegrin And Metalloproteinase Domain 17 (ADAM17/TACE).
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纯化方法
- Protein A Chromatography
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免疫原
- Recombinant protein, ADAM17 (NP_003174, 215 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: ADAM17
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亚型
- IgG2b
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anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) antibodyADAM17 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 201-300) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibodyADAM17 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyVerified ADAM17 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyKO Validated ADAM17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc) 宿主: 兔 Monoclonal 9E7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibodyADAM17 适用: 人 WB, ELISA, IHC, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (pThr735) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyADAM17 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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别名
- CD156b / ADAM17
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背景
- Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease.Synonyms: CSVP, Disintegrin and metalloproteinase domain-containing protein 17, Snake venom-like protease, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme
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基因ID
- 6868
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NCBI登录号
- NP_003174
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UniProt
- P78536
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
抗原
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